Promectin Plus Allwormer Item # 473
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Description
Promectin Plus combines Abamectin, a macrocylic lactone, with Praziquantel a
prazinoisoquinoline, in a palatable oatmeal flavoured paste.
Abamectin is a highly effective broad spectrum wormer with activity against gastrointestinal,
pulmonary and cutaneous nematodes, bots and external parasites. Abamectin acts by binding
selectively to glutamate gated chloride channels in invertebrate nerve and muscle cells causing
depolarisation of the nerve and muscle cells leading to paralysis and death of the parasites
Abamectin has good activity against both mature and immature stages of the nematodes. In the
horse, this is particularly of advantage and regular treatment will reduce the chances of
verminous arteritis and colic associated with Strongylus vulgaris. Abamectin has been
demonstrated to be safe when used at twice the recommended dose in foals, pregnant mares
and breeding stallions and up to 5 times the recommended dose in adults.
Praziquantel is a prazinoisoquinoline which is readily absorbed from the gastro-intestinal tract
and excreted in the bile and urine. Praziquantel has an extremely high activity against all
species of tapeworms. Praziquantel is absorbed readily and rapidly by Cestodes (tapeworms)
and causes a rapid tetanic spasm of the musculature of the parasite and vacuoles to appear in the tegument. In the tapeworm, there is first rapid contraction of the muscles and then a rise in the cell membrane calcium permeability which subsequently leads to muscle paralysis.
Praziquantel has been shown to have a wide safety margin.
Fax, Email, Mail Orders Quote Item # 473
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Fax:
Fax your order to 07 5546 3817 with the following information:
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Email:
Email your order to admin@centralhorsesales.com with the following information:
Name
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The items you wish to purchase including Item#, Quantity, Sizes/Colours (if applicable)



